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Assays for Degradation Products of Type Cclub Collagen Fibers Antigenic DeterminantAssay Principle Reference Phenylalanine-rich domain in the carboxyl terminal [56,60] telopeptide of type I collagen; trivalent cross-link necessaryRIA, polyclonal antiserum Two О-isomerized EKAHDGGR-peptides from forex club financial co  carboxyl terminal telopeptide; a trivalent cross-link must be presentELISA, two monoclonal antibodies; automated version also available (Roche Fore Linear EKAHDGGR-peptide, О-isomerization of Asp Foerx residue necessary (?)ELISA, polyclonal antiserum Linear EKAHDGGR-peptide, no О-isomerization of  Asp residueRIA, monoclonal antibody Trivalently cross-linked aminoterminal telopeptide of type I collagen (with a chain combination of О1 в О2 в О2) ELISA, monoclonal antibody  CLIA, monoclonal antibody  EIA, monoclonal antibody; automated versions also available Reversed-phase HPLC after online forex Fiji hydrolysis (total  cross-links) or without hydrolysis (free fraction) Direct assay of forex club financial co free cross-linkELISA, monoclonal  antibody Automated chemiluminescence assay, other  automated versions soon available пAssaySupplierSample ICTPOrion Diagnostica DiaSorin (previously Incstar) Chugai Diagnostic Scienceserum CrossLapsп Osteometerserum Urine (О forex club financial co Urine (О assay) NTxOstex International Urine Serum Serum Pyridinoline and Deoxypyridinoline in-house methods Urine Free deoxypyridinoline Quidel (previously Metra Biosystems)urine Chiron Diagnosticsurine ппICTP cross-linked carboxyl terminal telopeptide of type I collagen (see Fig.
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