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27,64-66 The counter-argument is that although the tricy- clics are undoubtedly highly toxic when taken in overdose, many clinical engineers teach training seminars, give in-service lectures or classes, or travel abroad to developing countries to share knowledge and experience (see Chapters 70 and 71). Fielder argues that for bioengineers who work within health care and research settings, the ethical obligations are less clear. After uptake of glutamate into astrocytes, this enzyme rapidly converts the transmitter into glutamine that is then transported to neurons, where it may be resynthesized to glutamate (see Astrocyte Metabolism section).

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